Smart Drug

Nootropics

Notes on Nootropics with evidence

Key resources

Studies on effectiveness of various Nootropics

Other notes

Caffeine

Ginseng

The information below is uncited - it would be good to collect links to specific studies to help assess which might be effective. ThufirHawat Citations are being added. *

: I advise reading them because I'm trying to include both supporting and detracting articles. Also, where info is sparse I include animal studies, and pathological studies - CassoX

Racetam Groups
Agent Mechanism Effect Dosage Citations
Piracetam mechanism effect 1600 mg - 9600 mg [5][6][7][8][9][10]
Aniracetam mechanism effect 750 mg - 1500 mg [11][12][13][14][15]
Oxiracetam mechanism effect 800mg - 1600mg [16][17][18][19][20][21]
Nefiracetam mechanism effect dosage [22]
Pramiracetam mechanism effect 200 mg - 400 mg [23]
Phenylpiracetam poorly characterized antiamnesia, psychostimulatory effect 100-200mg [24] [25]

Inhibitors
Agent Mechanism Effect Dosage Citations
Huperzine A Inhibits Acetylcholinesterase Increases Acetylcholine levels effect 50 mcg - 200 mcg [26]
Vinpocetine Inhibits Phospodiesterases Increases levels of cAMP, cGMP effect 5 mg - 10 mg [27]
Galantamine Inhibits Acetylcholinesterase Increases Acetylcholine levels Effect Dosage source
L-Deprenyl Inhibits MAO-B Increases Dopamine Levels Effect Dosage source
Tolcapone Inhibits COMT Increases Dopamine Levels Increases Epinephrine levels Increases Norepinephrine Levels Effect Dosage source
2C-E Inhibits MAO-B Increases Serotonin Stimulant at low doses Dose:5-10mg source

Neuroreceptor Agents
Agent Mechanism Effect Dosage Citations
Hydergine Stimulates dopaminergic and seratonergic receptors Inhibits Alpha Adrenoceptors Increases MAO levels effect dosage source

Neurotransmitter Precursors
Agent Mechanism Effect Dosage Citations
5-HTP Neurotransmitter precursor for Serotonin Increases serotonin levels effect dosage source
DMAE Neurotransmitter precursor for choline Increase Acetylcholine Levels effect dosage source
Centrophenoxine Neurotransmitter precursor for choline Increases acetylcholine levels Reduces Lipofuscins effect dosage source
Acetyl-L-Carnitine Neurotransmitter Precursor for Acetylcholine Effect Dosage source
Alpha-GPC Neurotransmitter Precursor for Choline Effect Dosage source
Choline Citrate Neurotransmitter Precursor for Acetylcholine Effect Dosage source
Choline Bitartrate Neurotransmitter Precursor for Acetylcholine Effect Dosage source
Citicoline Mechanism Effect Dosage source

Stimulants

StimulantsPrimer?
Agent Mechanism Effect Dosage Citations
Caffeine Mechanism Effect Dosage source
Ritalin Mechanism Effect Dosage source
Adderal Mechanism Effect Dosage source
Modanifil Mechanism Effect Dosage [28]
Ephedra Mechanism Effect Dosage source

Essential Nutrition

NutrientsPrimer?

Amino Acids

Essential
Amino Acid Function Dosage Citations
Isoleucine Function Dosage source
Leucine Function Dosage source
Lysine Function Dosage source
Methionine Function Dosage source
Phenylalanine Function Dosage source
Threonine Function Dosage source
Tryptophan Function Dosage source
Valine Function Dosage source
Arginine Function Dosage source
Histidine Function Dosage source

Nonessential
Amino Acid Function Dosage Citations
Alanine Function Dosage source
Asparagine Function Dosage source
Aspartate Function Dosage source
Cysteine Function Dosage source
Glutamate Function Dosage source
Glutamine Function Dosage source
Glycine Function Dosage source
Proline Function Dosage source
Serine Function Dosage source
Tyrosine Function Dosage source

Nonstandard
Amino Acid Function Dosage Citations
L-Dopa Neurotransmitter Precursor for Dopamine Increases Dopamine Levels Dosage source

Essential Fatty Acids

Essential Vitamins
Agent Mechanism Effect Dosage Citations
Pantothenic Acid Mechanism Effect Dosage source

Essential Minerals

Miscellaneous
Agent Mechanism Effect Dosage Citations
Ginko Biloba Mechanism Effect Dosage source
Ginseng Mechanism Effect Dosage source
Mucuna Pruriens Mechanism Effect Dosage source
Yohimbe Mechanism Effect Dosage source